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Chockalingam Ramanathan: Context-dependent inter-areal synchronization across mouse visual cortex

Institute of Physiology I [PhD Seminar]
When Mar 12, 2024
from 05:15 PM to 05:45 PM
Where Bernstein Center, Lecture Hall, ground floor, Hansastr. 9a
Contact Name
Contact Phone 0761 203 9549
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Abstract 

 
Most brain functions rely on constant interactions among specialized brain areas. In primates, synchronized oscillations in distinct frequency bands have been suggested to facilitate the routing of feedforward and feedback signals across hierarchically organized visual areas. However, the underlying mechanisms remain largely unknown. Previous studies in mice identified two distinct visually induced gamma rhythms: a luminance-dependent narrowband high gamma rhythm (~60Hz) in both V1 and higher visual areas and a context-dependent low gamma rhythm (~30Hz) in V1. To understand the properties and synchronisation of these oscillations across visual cortical areas, we performed simultaneous multi-areal Neuropixels recordings combined with causal optogenetic perturbations in retinotopically-matched locations in V1 and LM of awake, head-fixed mice. In this talk, I will be presenting some preliminary results indicating the role of feedforward entrainment in the generation of the visually induced oscillations in LM.

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Hosted by Samora Okujeni

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